Endosporinum - highly effective probiotic for cattle breeding as an alternative to antibiotics

POD Reference

TOUA20140912001

Summary

A university in Kyiv (Ukraine) offers an effective probiotic (endosporinum) for treatment and prevention of dysbiosis, intestinal and purulent infections, postpartum endometritis, retained of fetal membranes and other inflammatory diseases of genital ways of agricultural animals. The endosporinum stimulates protective immune response, inhibits pathogens, reduces convalescence time. Organization seeks of technical cooperation with companies that produce biological products.

Description

The endosporinum is a biopesticide that includes two strains of Bacillus subtilis, providing synergic effect in biological activities:

- High antagonistic activity against pathogenic and conditionally pathogenic microflora and preserving of normal intestinal flora;

- The ability to synthesize enzymes (cellulose, protease, lipase, amylase) that break down proteins, fats, carbohydrates, fiber and thus help to improve digestion and assimilation of feed;

- Production of aminoacids, including essential ones;

- The immunomodulating effect by increasing of synthesis of endogenous interferon and the functional activity of leukocytes and macrophages.

Manufacturing process includes: biomass production by deep cultivation method in fermenters using cheap components of the nutrient medium, and in the case of the dry form of the drug - lyophilic (sublimation) drying of culture liquid, packing in sterile vials, bottles or cans.

The endosporinum is effective as feed supplement for animals and birds. Use of the probiotic prevents gut-colonization by pathogenic microorganisms, increases non specific immunity, and contributes of growth of the animals’ weight and storing of livestock.

Advantages and Innovations

The probiotic allows to refuse the use of preventive antibiotics in livestock.

Probiotic has essential antimicrobial action. Unlike antibiotics, the bio-product does not cause formation of resistant strains of pathogenic bacteria.

Manufacturing of the probiotic does not require large capital expenses.

Use of the drug provides animal products which are safe for human health, competitive both in quality and price.

Stage of Development

Available for demonstration

IPR status

Patents granted
Secret Know-how

Comments Regarding IPR Status

Patents of Ukraine

Profile Origin

National R&D programme

Deadline Date

9/22/2015 12:00:00 AM

Technology Keywords

007001009 Veterinary Medicine

Market Keywords

007003002 Health food

Type and Role of Partner Sought

Type of partner sought: Investors, research and production companies engaged in the production of biological products.

Task to be performed by the partner sought:

production and distribution of drugs for livestock.

Task to be performed by the partner sought:

production and marketing of the drug.

Type and Size of Partner Sought

R&D Institution
SME 11-50
University

Type of Partnership Considered

Technical cooperation agreement